SEE THE
POWER OF
NATURE ITSELF

A natural evolution in aesthetics.

An applicator dispenses a droplet of ariessence pure PDGF+ topical solution

A safe, fast, and most predictable way to
pure CONFIDENCE.

ariessence pure PDGF+® is powered by the only proven growth factor available in aesthetics, driving rapid skin rejuvenation.

ariessence pure PDGF+ is a potent, cutting-edge, topical post-procedural enhancement that provides patients  with naturally beautiful and healthier-looking skin. It offers a quick, easy-to-use, consistent, and trusted approach to post-procedure skin rejuvenation, providing an exceptional patient experience.

Platelet-derived growth factor (PDGF): Nature’s rejuvenative protein, now in a topical solution.

ariessence pure PDGF+ topical solution is mixed between two syringes

We combine the benefits of one of the body’s most conserved proteins for skin rejuvenation, PDGF, with the soothing hydration of hyaluronic acid. When used following treatments including microneedling, RF microneedling, laser skin resurfacing, and peels, ariessence pure PDGF+ can enhance your patients’ results and reduce downtime.

Why ariessence?

In aesthetic rejuvenation,
no other product comes close.

ariessence pure PDGF+ is a complete game changer! In my practice, it has replaced PRP, PRF, and exosomes after microneedling and other large laser procedures. It is powerful, more predictable, and extremely easy to use.

Dr. Missy Clifton
Premier Dermatology

Our patients have reported exceptional satisfaction, noting significant improvements in skin vitality and rejuvenation.

Sarah Safa
P.A.
Refined Aesthetics

It takes less than one minute to mix pure PDGF+ with the HA serum! No blood draw is strongly preferred by clients and staff making ariessence much faster and less hassle.

Dawn Sagrillo
MSN, AGNP-BC, APNP, CANS
Refresh Aesthetics Center

Evolutionary solution.
Revolutionary results.

As a post-procedure topical application, ariessence pure PDGF+ is the ideal enhancement for a wide range of rejuvenative, aesthetic treatments.

Providers & patients report:

Reduction of post-procedure down time
Noticeable improvement in the appearance of glowing skin
Improved tone and texture in the appearance of the skin

ariessence applied post-microneedling.

Before
(baseline)

A photo of a woman post-microneedling, immediately after

Immediately
post-procedure

A photo of a woman post-microneedling, 1 hour after

1 hour
post-procedure

Photo of microneedling customer, 3 hours post-procedure

3 hour
post-procedure

A woman post-microneedling, one day after

1 day
post-procedure

Courtesy of Amanda Biradi, Advanced Nurse Injector

See More Before & Afters

Lynch SE, Huxel ST, Bond R, Biron J, Gold M. Recombinant Pure PDGF Improves Aesthetic Results and Patient Satisfaction Following RF Microneedling: A Prospective, Randomized, Controlled Clinical Trial. Journal of Cosmetic Dermatology. 2025 Sep;24(9):e70425. DOI: 10.1111/jocd.70425

Advanced skincare has evolved. We're leading the way.

Pure

The power of a naturally occurring growth factor in a topical solution with only four ingredients.

Faded back black and white closeup of the side of a woman's face

Potent

Up to 300,000x the concentration of growth factor of other aesthetic products.

Predictable

Pharmaceutical-grade PDGF. Provides a high-quality and consistent product, every time.

Proven

A recent clinical trial demonstrates the safety and benefits of pure PDGF. It is also used in 4 FDA-approved medical treatments (GEM 21S®, Augment®, Augment® Injectable, and Regranex®), and over 5.5 million patients have been treated with PDGF products in the last 28 years.*

Faded back black and white portrait of a woman

FDA approval of these products was based on each product’s own formulation, controls, extensive safety and effectiveness data, including data derived from blinded, randomized, controlled human clinical trials (i.e., pivotal studies) which were conducted independently from ariessence pure PDGF+®.

See how pure PDGF+
is transforming the
aesthetic space